Reference · cited facts
Tesamorelin
Egrifta / Egrifta SV / GHRH analogHalf-life ≈26–38 minutes (short)FDA-approvedReviewed July 2026
Educational information and a math tool only — not medical advice, a dose recommendation, or an endorsement of peptide use. Consult a licensed healthcare provider before starting, stopping, or changing anything.
Class / mechanism
Tesamorelin is a synthetic analog of growth-hormone-releasing hormone (GHRH); it signals the pituitary to release the body's own growth hormone rather than supplying growth hormone directly.
SOURCE [1]
Regulatory status
FDA-approved (initial U.S. approval 2010) for the reduction of excess visceral abdominal fat in adults with HIV-associated lipodystrophy — that is its only FDA-approved indication. Prescription only. Supplied as a lyophilized powder that is reconstituted before subcutaneous injection. As of 2026-07-16 and subject to change.
FDA · July 2026
Reported half-life
≈26–38 minutes (short)
PUBMED
Human evidence
Established (FDA-approved)
LITERATURE
What the literature reports
- Tesamorelin is a synthetic analog of growth-hormone-releasing hormone (GHRH); it signals the pituitary to release the body's own growth hormone rather than supplying growth hormone directly.
- It is FDA-approved (2010) for one indication — reducing excess visceral abdominal fat in adults with HIV-associated lipodystrophy. The brand names Egrifta, Egrifta SV and Egrifta WR are used for identification only.
- The FDA-approved product is supplied as a lyophilized (freeze-dried) powder that is reconstituted with a sterile diluent before injection, so the reconstitution math applies to the approved product itself.
- Its blood half-life is short — reported as roughly 26–38 minutes — consistent with the rapid absorption the FDA prescribing information describes.
Honest caveats
- • This is a prescription medicine — obtain and use it only through a licensed clinician.
- • It is FDA-approved for a single indication (HIV-associated lipodystrophy); this page states that indication as a neutral fact and makes no recommendation for any use.
- • Reference facts only — no dose, protocol, or benefit is stated or implied.
Reconstitution calculator
Enter your own vial size, BAC water and target dose — get exact syringe units.
Sources